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WASH complex subunit 3 (WASHC3)

Homo sapiens — UniProt Q9Y3C0

Gene: WASHC3Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

WASH complex subunit 3 (WASHC3) is a protein from Homo sapiens identified by UniProt accession Q9Y3C0, 194 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.

  • UniProt accession: Q9Y3C0; gene symbol WASHC3.
  • Organism: Homo sapiens.
  • Length: 194 amino acids.
  • Top disease associations (Open Targets): lean body mass, body height and appendicular lean mass.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameWASH complex subunit 3
UniProt accessionQ9Y3C0
GeneWASHC3
OrganismHomo sapiens
Length194 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (38)

Diseases linked to this target (Open Targets).

  • lean body mass · score 0.47
  • body height · score 0.42
  • appendicular lean mass · score 0.41
  • fat body mass · score 0.39
  • whole body water mass · score 0.34
  • base metabolic rate measurement · score 0.34
  • sitting height measurement · score 0.32
  • BMI-adjusted hip circumference · score 0.31
  • body weight · score 0.29
  • IGF-1 measurement · score 0.21

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9Y3C0-F1alphafoldPREDICTED70.03—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y3C0.

Amino-acid sequence (194 residues)

MDEDGLPLMG SGIDLTKVPA IQQKRTVAFL NQFVVHTVQF LNRFSTVCEE KLADLSLRIQ QIETTLNILD AKLSSIPGLD DVTVEVSPLN VTSVTNGAHP EATSEQPQQN STQDSGLQES EVSAENILTV AKDPRYARYL KMVQVGVPVM AIRNKMISEG LDPDLLERPD APVPDGESEK TVEESSDSES SFSD

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with WASHC3?

The strongest Open Targets associations for WASHC3 are lean body mass, body height, appendicular lean mass, fat body mass and whole body water mass.

How long is the WASHC3 protein?

The Homo sapiens WASHC3 protein (UniProt Q9Y3C0) is 194 amino acids long.

Browse: Targets: W · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9Y3C0
GeneWASHC3
OrganismHomo sapiens
Length194
Binders0
Diseases38
View on UniProt