Nucleolar protein 16 (NOP16)
Homo sapiens — UniProt Q9Y3C1
Data last refreshed: (UniProt release unknown)
Key facts
Nucleolar protein 16 (NOP16) is a protein from Homo sapiens identified by UniProt accession Q9Y3C1, 178 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.
- UniProt accession: Q9Y3C1; gene symbol NOP16.
- Organism: Homo sapiens.
- Length: 178 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Parkinson disease and lysosomal storage disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Nucleolar protein 16 |
|---|---|
| UniProt accession | Q9Y3C1 |
| Gene | NOP16 |
| Organism | Homo sapiens |
| Length | 178 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (28)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.47
- Parkinson disease · score 0.46
- lysosomal storage disease · score 0.46
- Alzheimer disease · score 0.46
- multiple sclerosis · score 0.46
- gonorrhea · score 0.07
- gut microbiome measurement · score 0.07
- cancer · score 0.03
- neoplasm · score 0.03
- systemic juvenile idiopathic arthritis · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y3C1-F1 | alphafold | PREDICTED | 85.52 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y3C1.
Amino-acid sequence (178 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NOP16?
The strongest Open Targets associations for NOP16 are neurodegenerative disease, Parkinson disease, lysosomal storage disease, Alzheimer disease and multiple sclerosis.
How long is the NOP16 protein?
The Homo sapiens NOP16 protein (UniProt Q9Y3C1) is 178 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y3C1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y3C1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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