RING finger protein 11 (RNF11)
Homo sapiens — UniProt Q9Y3C5
Data last refreshed: (UniProt release unknown)
Key facts
RING finger protein 11 (RNF11) is a protein from Homo sapiens identified by UniProt accession Q9Y3C5, 154 residues long. MolForge cross-references it against 0 known binders and 51 disease associations.
- UniProt accession: Q9Y3C5; gene symbol RNF11.
- Organism: Homo sapiens.
- Length: 154 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, brain volume measurement and mean corpuscular volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | RING finger protein 11 |
|---|---|
| UniProt accession | Q9Y3C5 |
| Gene | RNF11 |
| Organism | Homo sapiens |
| Length | 154 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (51)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.31
- brain volume measurement · score 0.20
- mean corpuscular volume · score 0.15
- gut microbiome measurement · score 0.15
- blood urea nitrogen measurement · score 0.14
- erythrocyte count · score 0.10
- calcium measurement · score 0.09
- blood phosphate measurement · score 0.07
- hepatocellular carcinoma · score 0.05
- QRS duration · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y3C5-F1 | alphafold | PREDICTED | 78.39 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y3C5.
Amino-acid sequence (154 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RNF11?
The strongest Open Targets associations for RNF11 are neurodegenerative disease, brain volume measurement, mean corpuscular volume, gut microbiome measurement and blood urea nitrogen measurement.
How long is the RNF11 protein?
The Homo sapiens RNF11 protein (UniProt Q9Y3C5) is 154 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y3C5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y3C5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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