Mediator of RNA polymerase II transcription subunit 31 (MED31)
Homo sapiens — UniProt Q9Y3C7
Data last refreshed: (UniProt release unknown)
Key facts
Mediator of RNA polymerase II transcription subunit 31 (MED31) is a protein from Homo sapiens identified by UniProt accession Q9Y3C7, 131 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: Q9Y3C7; gene symbol MED31.
- Organism: Homo sapiens.
- Length: 131 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, pulse pressure measurement and systolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Mediator of RNA polymerase II transcription subunit 31 |
|---|---|
| UniProt accession | Q9Y3C7 |
| Gene | MED31 |
| Organism | Homo sapiens |
| Length | 131 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- pulse pressure measurement · score 0.12
- systolic blood pressure · score 0.09
- body height · score 0.07
- forced expiratory volume · score 0.05
- diastolic blood pressure · score 0.04
- heel bone mineral density · score 0.04
- BMI-adjusted waist circumference · score 0.04
- lymphatic malformation 8 · score 0.03
- visual perception measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y3C7-F1 | alphafold | PREDICTED | 92.88 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y3C7.
Amino-acid sequence (131 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MED31?
The strongest Open Targets associations for MED31 are neurodegenerative disease, pulse pressure measurement, systolic blood pressure, body height and forced expiratory volume.
How long is the MED31 protein?
The Homo sapiens MED31 protein (UniProt Q9Y3C7) is 131 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y3C7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y3C7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.