Small ribosomal subunit protein bS16m (MRPS16)
Homo sapiens — UniProt Q9Y3D3
Data last refreshed: (UniProt release unknown)
Key facts
Small ribosomal subunit protein bS16m (MRPS16) is a protein from Homo sapiens identified by UniProt accession Q9Y3D3, 137 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.
- UniProt accession: Q9Y3D3; gene symbol MRPS16.
- Organism: Homo sapiens.
- Length: 137 amino acids.
- Top disease associations (Open Targets): combined oxidative phosphorylation defect type 2, neurodegenerative disease and combined oxidative phosphorylation deficiency.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Small ribosomal subunit protein bS16m |
|---|---|
| UniProt accession | Q9Y3D3 |
| Gene | MRPS16 |
| Organism | Homo sapiens |
| Length | 137 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (18)
Diseases linked to this target (Open Targets).
- combined oxidative phosphorylation defect type 2 · score 0.52
- neurodegenerative disease · score 0.50
- combined oxidative phosphorylation deficiency · score 0.18
- neoplasm · score 0.09
- diastolic blood pressure · score 0.03
- glomerular filtration rate · score 0.03
- reticulocyte measurement · score 0.03
- serum alanine aminotransferase measurement · score 0.03
- systemic juvenile idiopathic arthritis · score 0.01
- cancer · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y3D3-F1 | alphafold | PREDICTED | 90.64 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y3D3.
Amino-acid sequence (137 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MRPS16?
The strongest Open Targets associations for MRPS16 are combined oxidative phosphorylation defect type 2, neurodegenerative disease, combined oxidative phosphorylation deficiency, neoplasm and diastolic blood pressure.
How long is the MRPS16 protein?
The Homo sapiens MRPS16 protein (UniProt Q9Y3D3) is 137 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y3D3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y3D3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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