Small ribosomal subunit protein bS18m (MRPS18C)
Homo sapiens — UniProt Q9Y3D5
Data last refreshed: (UniProt release unknown)
Key facts
Small ribosomal subunit protein bS18m (MRPS18C) is a protein from Homo sapiens identified by UniProt accession Q9Y3D5, 142 residues long. MolForge cross-references it against 0 known binders and 70 disease associations.
- UniProt accession: Q9Y3D5; gene symbol MRPS18C.
- Organism: Homo sapiens.
- Length: 142 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Inherited cancer-predisposing syndrome and hereditary neoplastic syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Small ribosomal subunit protein bS18m |
|---|---|
| UniProt accession | Q9Y3D5 |
| Gene | MRPS18C |
| Organism | Homo sapiens |
| Length | 142 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (70)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- Inherited cancer-predisposing syndrome · score 0.40
- hereditary neoplastic syndrome · score 0.40
- hereditary breast ovarian cancer syndrome · score 0.17
- Hereditary breast and ovarian cancer syndrome · score 0.17
- age at menopause · score 0.15
- genetic disorder · score 0.12
- breast cancer · score 0.12
- Blackfan-Diamond anemia · score 0.07
- hemoglobin E-beta-thalassemia syndrome · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y3D5-F1 | alphafold | PREDICTED | 79.42 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y3D5.
Amino-acid sequence (142 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MRPS18C?
The strongest Open Targets associations for MRPS18C are neurodegenerative disease, Inherited cancer-predisposing syndrome, hereditary neoplastic syndrome, hereditary breast ovarian cancer syndrome and Hereditary breast and ovarian cancer syndrome.
How long is the MRPS18C protein?
The Homo sapiens MRPS18C protein (UniProt Q9Y3D5) is 142 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y3D5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y3D5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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