Adenylate kinase isoenzyme 6 (AK6)
Homo sapiens — UniProt Q9Y3D8
Data last refreshed: (UniProt release unknown)
Key facts
Adenylate kinase isoenzyme 6 (AK6) is a protein from Homo sapiens identified by UniProt accession Q9Y3D8, 172 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.
- UniProt accession: Q9Y3D8; gene symbol AK6.
- Organism: Homo sapiens.
- Length: 172 amino acids.
- Top disease associations (Open Targets): glomerular filtration rate, neoplasm and uric acid measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Adenylate kinase isoenzyme 6 |
|---|---|
| UniProt accession | Q9Y3D8 |
| Gene | AK6 |
| Organism | Homo sapiens |
| Length | 172 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- glomerular filtration rate · score 0.13
- neoplasm · score 0.09
- uric acid measurement · score 0.09
- cancer · score 0.08
- acute myeloid leukemia · score 0.08
- interleukin 18 measurement · score 0.07
- blood urea nitrogen measurement · score 0.05
- urate measurement · score 0.05
- Anisometropia · score 0.05
- Aniseikonia · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y3D8-F1 | alphafold | PREDICTED | 97.16 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y3D8.
Amino-acid sequence (172 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with AK6?
The strongest Open Targets associations for AK6 are glomerular filtration rate, neoplasm, uric acid measurement, cancer and acute myeloid leukemia.
How long is the AK6 protein?
The Homo sapiens AK6 protein (UniProt Q9Y3D8) is 172 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y3D8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y3D8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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