Vesicle transport protein GOT1B (GOLT1B)
Homo sapiens — UniProt Q9Y3E0
Data last refreshed: (UniProt release unknown)
Key facts
Vesicle transport protein GOT1B (GOLT1B) is a protein from Homo sapiens identified by UniProt accession Q9Y3E0, 138 residues long. MolForge cross-references it against 0 known binders and 66 disease associations.
- UniProt accession: Q9Y3E0; gene symbol GOLT1B.
- Organism: Homo sapiens.
- Length: 138 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, cancer and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Vesicle transport protein GOT1B |
|---|---|
| UniProt accession | Q9Y3E0 |
| Gene | GOLT1B |
| Organism | Homo sapiens |
| Length | 138 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (66)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.45
- cancer · score 0.08
- neoplasm · score 0.08
- platelet count · score 0.06
- Wolff-Parkinson-White Syndrome · score 0.04
- Brugada syndrome · score 0.04
- familial sick sinus syndrome · score 0.03
- trimethylaminuria · score 0.03
- Trimethylaminuria · score 0.03
- atrial conduction disease · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y3E0-F1 | alphafold | PREDICTED | 88.20 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y3E0.
Amino-acid sequence (138 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GOLT1B?
The strongest Open Targets associations for GOLT1B are neurodegenerative disease, cancer, neoplasm, platelet count and Wolff-Parkinson-White Syndrome.
How long is the GOLT1B protein?
The Homo sapiens GOLT1B protein (UniProt Q9Y3E0) is 138 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y3E0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y3E0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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