BolA-like protein 1 (BOLA1)
Homo sapiens — UniProt Q9Y3E2
Data last refreshed: (UniProt release unknown)
Key facts
BolA-like protein 1 (BOLA1) is a protein from Homo sapiens identified by UniProt accession Q9Y3E2, 137 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.
- UniProt accession: Q9Y3E2; gene symbol BOLA1.
- Organism: Homo sapiens.
- Length: 137 amino acids.
- Top disease associations (Open Targets): triglyceride measurement, lymphocyte percentage of leukocytes and sex hormone-binding globulin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | BolA-like protein 1 |
|---|---|
| UniProt accession | Q9Y3E2 |
| Gene | BOLA1 |
| Organism | Homo sapiens |
| Length | 137 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (27)
Diseases linked to this target (Open Targets).
- triglyceride measurement · score 0.15
- lymphocyte percentage of leukocytes · score 0.12
- sex hormone-binding globulin measurement · score 0.09
- neutrophil count · score 0.08
- forced expiratory volume · score 0.08
- high density lipoprotein cholesterol measurement · score 0.06
- monocyte count · score 0.06
- type 2 diabetes mellitus · score 0.06
- interleukin 6 receptor subunit alpha measurement · score 0.05
- apolipoprotein A 1 measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y3E2-F1 | alphafold | PREDICTED | 76.91 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y3E2.
Amino-acid sequence (137 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BOLA1?
The strongest Open Targets associations for BOLA1 are triglyceride measurement, lymphocyte percentage of leukocytes, sex hormone-binding globulin measurement, neutrophil count and forced expiratory volume.
How long is the BOLA1 protein?
The Homo sapiens BOLA1 protein (UniProt Q9Y3E2) is 137 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y3E2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y3E2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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