Charged multivesicular body protein 3 (CHMP3)
Homo sapiens — UniProt Q9Y3E7
Data last refreshed: (UniProt release unknown)
Key facts
Charged multivesicular body protein 3 (CHMP3) is a protein from Homo sapiens identified by UniProt accession Q9Y3E7, 222 residues long. MolForge cross-references it against 0 known binders and 105 disease associations.
- UniProt accession: Q9Y3E7; gene symbol CHMP3.
- Organism: Homo sapiens.
- Length: 222 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, viral disease and HIV infection.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Charged multivesicular body protein 3 |
|---|---|
| UniProt accession | Q9Y3E7 |
| Gene | CHMP3 |
| Organism | Homo sapiens |
| Length | 222 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (105)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- viral disease · score 0.46
- HIV infection · score 0.46
- COVID-19 · score 0.37
- severe acute respiratory syndrome · score 0.37
- body mass index · score 0.36
- neuroticism measurement · score 0.32
- unipolar depression · score 0.31
- blood protein measurement · score 0.25
- wellbeing measurement · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y3E7-F1 | alphafold | PREDICTED | 81.36 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y3E7.
Amino-acid sequence (222 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CHMP3?
The strongest Open Targets associations for CHMP3 are neurodegenerative disease, viral disease, HIV infection, COVID-19 and severe acute respiratory syndrome.
How long is the CHMP3 protein?
The Homo sapiens CHMP3 protein (UniProt Q9Y3E7) is 222 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y3E7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y3E7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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