F-box only protein 7 (FBXO7)
Homo sapiens — UniProt Q9Y3I1
Data last refreshed: (UniProt release unknown)
Key facts
F-box only protein 7 (FBXO7) is a protein from Homo sapiens identified by UniProt accession Q9Y3I1, 522 residues long. MolForge cross-references it against 0 known binders and 368 disease associations.
- UniProt accession: Q9Y3I1; gene symbol FBXO7.
- Organism: Homo sapiens.
- Length: 522 amino acids.
- Top disease associations (Open Targets): parkinsonian-pyramidal syndrome, Parkinson disease and Dystonia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | F-box only protein 7 |
|---|---|
| UniProt accession | Q9Y3I1 |
| Gene | FBXO7 |
| Organism | Homo sapiens |
| Length | 522 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (368)
Diseases linked to this target (Open Targets).
- parkinsonian-pyramidal syndrome · score 0.78
- Parkinson disease · score 0.57
- Dystonia · score 0.50
- mean corpuscular volume · score 0.33
- mean corpuscular hemoglobin · score 0.32
- Red cell distribution width · score 0.29
- mean corpuscular hemoglobin concentration · score 0.28
- red blood cell density measurement · score 0.27
- erythrocyte count · score 0.25
- mean reticulocyte volume · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y3I1-F1 | alphafold | PREDICTED | 66.43 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y3I1.
Amino-acid sequence (522 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FBXO7?
The strongest Open Targets associations for FBXO7 are parkinsonian-pyramidal syndrome, Parkinson disease, Dystonia, mean corpuscular volume and mean corpuscular hemoglobin.
How long is the FBXO7 protein?
The Homo sapiens FBXO7 protein (UniProt Q9Y3I1) is 522 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y3I1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y3I1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.