Ras-related protein Rap-2c (RAP2C)
Homo sapiens — UniProt Q9Y3L5
Data last refreshed: (UniProt release unknown)
Key facts
Ras-related protein Rap-2c (RAP2C) is a protein from Homo sapiens identified by UniProt accession Q9Y3L5, 183 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.
- UniProt accession: Q9Y3L5; gene symbol RAP2C.
- Organism: Homo sapiens.
- Length: 183 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, alkaline phosphatase measurement and nail-patella syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ras-related protein Rap-2c |
|---|---|
| UniProt accession | Q9Y3L5 |
| Gene | RAP2C |
| Organism | Homo sapiens |
| Length | 183 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (31)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- alkaline phosphatase measurement · score 0.10
- nail-patella syndrome · score 0.07
- small cell lung carcinoma · score 0.07
- uterine fibroid · score 0.04
- Uterine leiomyoma · score 0.03
- neoplasm · score 0.02
- lumbar disc degeneration · score 0.02
- bladder transitional cell carcinoma · score 0.02
- cancer · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y3L5-F1 | alphafold | PREDICTED | 91.18 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y3L5.
Amino-acid sequence (183 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RAP2C?
The strongest Open Targets associations for RAP2C are neurodegenerative disease, alkaline phosphatase measurement, nail-patella syndrome, small cell lung carcinoma and uterine fibroid.
How long is the RAP2C protein?
The Homo sapiens RAP2C protein (UniProt Q9Y3L5) is 183 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y3L5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y3L5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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