N-acetylated-alpha-linked acidic dipeptidase 2 (NAALAD2)
Homo sapiens — UniProt Q9Y3Q0
Data last refreshed: (UniProt release unknown)
Key facts
N-acetylated-alpha-linked acidic dipeptidase 2 (NAALAD2) is a protein from Homo sapiens identified by UniProt accession Q9Y3Q0, 740 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.
- UniProt accession: Q9Y3Q0; gene symbol NAALAD2.
- Organism: Homo sapiens.
- Length: 740 amino acids.
- Top disease associations (Open Targets): body mass index, serum metabolite measurement and body fat percentage.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | N-acetylated-alpha-linked acidic dipeptidase 2 |
|---|---|
| UniProt accession | Q9Y3Q0 |
| Gene | NAALAD2 |
| Organism | Homo sapiens |
| Length | 740 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (47)
Diseases linked to this target (Open Targets).
- body mass index · score 0.41
- serum metabolite measurement · score 0.37
- body fat percentage · score 0.36
- fat body mass · score 0.36
- basophil count · score 0.34
- urinary metabolite measurement · score 0.34
- body height · score 0.23
- visceral adipose tissue measurement · score 0.22
- lean body mass · score 0.22
- mathematical ability · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y3Q0-F1 | alphafold | PREDICTED | 95.09 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y3Q0.
Amino-acid sequence (740 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NAALAD2?
The strongest Open Targets associations for NAALAD2 are body mass index, serum metabolite measurement, body fat percentage, fat body mass and basophil count.
How long is the NAALAD2 protein?
The Homo sapiens NAALAD2 protein (UniProt Q9Y3Q0) is 740 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y3Q0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y3Q0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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