Transmembrane emp24 domain-containing protein 3 (TMED3)
Homo sapiens — UniProt Q9Y3Q3
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane emp24 domain-containing protein 3 (TMED3) is a protein from Homo sapiens identified by UniProt accession Q9Y3Q3, 217 residues long. MolForge cross-references it against 0 known binders and 55 disease associations.
- UniProt accession: Q9Y3Q3; gene symbol TMED3.
- Organism: Homo sapiens.
- Length: 217 amino acids.
- Top disease associations (Open Targets): central corneal thickness, neoplasm and blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane emp24 domain-containing protein 3 |
|---|---|
| UniProt accession | Q9Y3Q3 |
| Gene | TMED3 |
| Organism | Homo sapiens |
| Length | 217 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (55)
Diseases linked to this target (Open Targets).
- central corneal thickness · score 0.19
- neoplasm · score 0.10
- blood protein measurement · score 0.09
- testosterone measurement · score 0.08
- hepatocellular carcinoma · score 0.08
- Chordoma · score 0.07
- Miyoshi myopathy · score 0.07
- esophageal squamous cell carcinoma · score 0.07
- neurofibrillary tangles measurement · score 0.06
- melanoma · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y3Q3-F1 | alphafold | PREDICTED | 88.02 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y3Q3.
Amino-acid sequence (217 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMED3?
The strongest Open Targets associations for TMED3 are central corneal thickness, neoplasm, blood protein measurement, testosterone measurement and hepatocellular carcinoma.
How long is the TMED3 protein?
The Homo sapiens TMED3 protein (UniProt Q9Y3Q3) is 217 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y3Q3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y3Q3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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