TSC22 domain family protein 4 (TSC22D4)
Homo sapiens — UniProt Q9Y3Q8
Data last refreshed: (UniProt release unknown)
Key facts
TSC22 domain family protein 4 (TSC22D4) is a protein from Homo sapiens identified by UniProt accession Q9Y3Q8, 395 residues long. MolForge cross-references it against 0 known binders and 52 disease associations.
- UniProt accession: Q9Y3Q8; gene symbol TSC22D4.
- Organism: Homo sapiens.
- Length: 395 amino acids.
- Top disease associations (Open Targets): Red cell distribution width, neurodegenerative disease and platelet component distribution width.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | TSC22 domain family protein 4 |
|---|---|
| UniProt accession | Q9Y3Q8 |
| Gene | TSC22D4 |
| Organism | Homo sapiens |
| Length | 395 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (52)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.37
- neurodegenerative disease · score 0.34
- platelet component distribution width · score 0.20
- platelet count · score 0.18
- self reported educational attainment · score 0.15
- platelet crit · score 0.14
- monocyte count · score 0.13
- heel bone mineral density · score 0.12
- mean platelet volume · score 0.06
- neoplasm · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y3Q8-F1 | alphafold | PREDICTED | 56.91 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y3Q8.
Amino-acid sequence (395 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TSC22D4?
The strongest Open Targets associations for TSC22D4 are Red cell distribution width, neurodegenerative disease, platelet component distribution width, platelet count and self reported educational attainment.
How long is the TSC22D4 protein?
The Homo sapiens TSC22D4 protein (UniProt Q9Y3Q8) is 395 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y3Q8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y3Q8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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