Glutamate receptor-interacting protein 1 (GRIP1)
Homo sapiens — UniProt Q9Y3R0
Data last refreshed: (UniProt release unknown)
Key facts
Glutamate receptor-interacting protein 1 (GRIP1) is a protein from Homo sapiens identified by UniProt accession Q9Y3R0, 1128 residues long. MolForge cross-references it against 0 known binders and 199 disease associations.
- UniProt accession: Q9Y3R0; gene symbol GRIP1.
- Organism: Homo sapiens.
- Length: 1128 amino acids.
- Top disease associations (Open Targets): Fraser syndrome, polydactyly and Polydactyly.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Glutamate receptor-interacting protein 1 |
|---|---|
| UniProt accession | Q9Y3R0 |
| Gene | GRIP1 |
| Organism | Homo sapiens |
| Length | 1128 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (199)
Diseases linked to this target (Open Targets).
- Fraser syndrome · score 0.77
- polydactyly · score 0.37
- Polydactyly · score 0.37
- protein measurement · score 0.36
- PHF-tau measurement · score 0.34
- cortical thickness · score 0.30
- cortical surface area measurement · score 0.30
- Abnormal brain morphology · score 0.29
- intestinal disease · score 0.29
- brain measurement · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y3R0-F1 | alphafold | PREDICTED | 61.65 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y3R0.
Amino-acid sequence (1128 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GRIP1?
The strongest Open Targets associations for GRIP1 are Fraser syndrome, polydactyly, Polydactyly, protein measurement and PHF-tau measurement.
How long is the GRIP1 protein?
The Homo sapiens GRIP1 protein (UniProt Q9Y3R0) is 1128 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y3R0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y3R0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.