R3H and coiled-coil domain-containing protein 1 (R3HCC1)
Homo sapiens — UniProt Q9Y3T6
Data last refreshed: (UniProt release unknown)
Key facts
R3H and coiled-coil domain-containing protein 1 (R3HCC1) is a protein from Homo sapiens identified by UniProt accession Q9Y3T6, 440 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: Q9Y3T6; gene symbol R3HCC1.
- Organism: Homo sapiens.
- Length: 440 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, lean body mass and PHF-tau measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | R3H and coiled-coil domain-containing protein 1 |
|---|---|
| UniProt accession | Q9Y3T6 |
| Gene | R3HCC1 |
| Organism | Homo sapiens |
| Length | 440 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.27
- lean body mass · score 0.24
- PHF-tau measurement · score 0.22
- fat body mass · score 0.12
- base metabolic rate measurement · score 0.12
- whole body water mass · score 0.09
- body height · score 0.07
- appendicular lean mass · score 0.06
- forced expiratory volume · score 0.05
- sitting height measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y3T6-F1 | alphafold | PREDICTED | 65.96 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y3T6.
Amino-acid sequence (440 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with R3HCC1?
The strongest Open Targets associations for R3HCC1 are neurodegenerative disease, lean body mass, PHF-tau measurement, fat body mass and base metabolic rate measurement.
How long is the R3HCC1 protein?
The Homo sapiens R3HCC1 protein (UniProt Q9Y3T6) is 440 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y3T6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y3T6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.