Large ribosomal subunit protein eL36 (RPL36)
Homo sapiens — UniProt Q9Y3U8
Data last refreshed: (UniProt release unknown)
Key facts
Large ribosomal subunit protein eL36 (RPL36) is a protein from Homo sapiens identified by UniProt accession Q9Y3U8, 105 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.
- UniProt accession: Q9Y3U8; gene symbol RPL36.
- Organism: Homo sapiens.
- Length: 105 amino acids.
- Top disease associations (Open Targets): Duchenne muscular dystrophy, cystic fibrosis and Diamond-Blackfan anemia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Large ribosomal subunit protein eL36 |
|---|---|
| UniProt accession | Q9Y3U8 |
| Gene | RPL36 |
| Organism | Homo sapiens |
| Length | 105 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (47)
Diseases linked to this target (Open Targets).
- Duchenne muscular dystrophy · score 0.50
- cystic fibrosis · score 0.50
- Diamond-Blackfan anemia · score 0.46
- influenza · score 0.46
- combined oxidative phosphorylation deficiency · score 0.45
- genetic disorder · score 0.32
- Becker muscular dystrophy · score 0.29
- qualitative or quantitative defects of dystrophin · score 0.26
- Red cell distribution width · score 0.11
- myoepithelial tumor · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y3U8-F1 | alphafold | PREDICTED | 93.15 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y3U8.
Amino-acid sequence (105 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RPL36?
The strongest Open Targets associations for RPL36 are Duchenne muscular dystrophy, cystic fibrosis, Diamond-Blackfan anemia, influenza and combined oxidative phosphorylation deficiency.
How long is the RPL36 protein?
The Homo sapiens RPL36 protein (UniProt Q9Y3U8) is 105 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y3U8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y3U8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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