Zonadhesin (ZAN)
Homo sapiens — UniProt Q9Y493
Data last refreshed: (UniProt release unknown)
Key facts
Zonadhesin (ZAN) is a protein from Homo sapiens identified by UniProt accession Q9Y493, 2812 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.
- UniProt accession: Q9Y493; gene symbol ZAN.
- Organism: Homo sapiens.
- Length: 2812 amino acids.
- Top disease associations (Open Targets): erythrocyte count, red blood cell density measurement and mean corpuscular hemoglobin.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zonadhesin |
|---|---|
| UniProt accession | Q9Y493 |
| Gene | ZAN |
| Organism | Homo sapiens |
| Length | 2812 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (45)
Diseases linked to this target (Open Targets).
- erythrocyte count · score 0.36
- red blood cell density measurement · score 0.32
- mean corpuscular hemoglobin · score 0.28
- hemoglobin measurement · score 0.27
- total cholesterol measurement · score 0.26
- mean corpuscular volume · score 0.26
- heel bone mineral density · score 0.18
- mean platelet volume · score 0.17
- white matter hyperintensity measurement · score 0.17
- Red cell distribution width · score 0.17
3D Structure (9)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y493-F6 | alphafold | PREDICTED | 80.02 | — |
| AF-Q9Y493-F7 | alphafold | PREDICTED | 79.88 | — |
| AF-Q9Y493-F9 | alphafold | PREDICTED | 74.89 | — |
| AF-Q9Y493-F8 | alphafold | PREDICTED | 73.74 | — |
| AF-Q9Y493-F5 | alphafold | PREDICTED | 73.42 | — |
| AF-Q9Y493-F4 | alphafold | PREDICTED | 66.87 | — |
| AF-Q9Y493-F3 | alphafold | PREDICTED | 64.36 | — |
| AF-Q9Y493-F2 | alphafold | PREDICTED | 63.97 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y493.
Amino-acid sequence (2812 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZAN?
The strongest Open Targets associations for ZAN are erythrocyte count, red blood cell density measurement, mean corpuscular hemoglobin, hemoglobin measurement and total cholesterol measurement.
How long is the ZAN protein?
The Homo sapiens ZAN protein (UniProt Q9Y493) is 2812 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y493 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y493 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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