Kinesin-like protein KIF3A (KIF3A)
Homo sapiens — UniProt Q9Y496
Data last refreshed: (UniProt release unknown)
Key facts
Kinesin-like protein KIF3A (KIF3A) is a protein from Homo sapiens identified by UniProt accession Q9Y496, 699 residues long. MolForge cross-references it against 0 known binders and 118 disease associations.
- UniProt accession: Q9Y496; gene symbol KIF3A.
- Organism: Homo sapiens.
- Length: 699 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, mood disorder and atopic eczema.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Kinesin-like protein KIF3A |
|---|---|
| UniProt accession | Q9Y496 |
| Gene | KIF3A |
| Organism | Homo sapiens |
| Length | 699 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (118)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- mood disorder · score 0.33
- atopic eczema · score 0.29
- depressive disorder · score 0.26
- childhood onset asthma · score 0.22
- ovarian cancer · score 0.18
- breast adenocarcinoma · score 0.18
- allergic disease · score 0.18
- Abnormality of refraction · score 0.18
- asthma · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y496-F1 | alphafold | PREDICTED | 75.45 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y496.
Amino-acid sequence (699 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KIF3A?
The strongest Open Targets associations for KIF3A are neurodegenerative disease, mood disorder, atopic eczema, depressive disorder and childhood onset asthma.
How long is the KIF3A protein?
The Homo sapiens KIF3A protein (UniProt Q9Y496) is 699 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y496 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y496 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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