Jerky protein homolog-like (JRKL)
Homo sapiens — UniProt Q9Y4A0
Data last refreshed: (UniProt release unknown)
Key facts
Jerky protein homolog-like (JRKL) is a protein from Homo sapiens identified by UniProt accession Q9Y4A0, 524 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.
- UniProt accession: Q9Y4A0; gene symbol JRKL.
- Organism: Homo sapiens.
- Length: 524 amino acids.
- Top disease associations (Open Targets): mathematical ability, monocyte count and metabolite measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Jerky protein homolog-like |
|---|---|
| UniProt accession | Q9Y4A0 |
| Gene | JRKL |
| Organism | Homo sapiens |
| Length | 524 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (27)
Diseases linked to this target (Open Targets).
- mathematical ability · score 0.18
- monocyte count · score 0.17
- metabolite measurement · score 0.17
- lean body mass · score 0.09
- lymphocyte count · score 0.08
- hematocrit · score 0.07
- hemoglobin measurement · score 0.06
- red blood cell density measurement · score 0.05
- hypertension · score 0.05
- mean corpuscular hemoglobin · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y4A0-F1 | alphafold | PREDICTED | 78.98 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y4A0.
Amino-acid sequence (524 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with JRKL?
The strongest Open Targets associations for JRKL are mathematical ability, monocyte count, metabolite measurement, lean body mass and lymphocyte count.
How long is the JRKL protein?
The Homo sapiens JRKL protein (UniProt Q9Y4A0) is 524 amino acids long.
Browse: Targets: J · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y4A0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y4A0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.