Helicase ARIP4 (RAD54L2)
Homo sapiens — UniProt Q9Y4B4
Data last refreshed: (UniProt release unknown)
Key facts
Helicase ARIP4 (RAD54L2) is a protein from Homo sapiens identified by UniProt accession Q9Y4B4, 1467 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.
- UniProt accession: Q9Y4B4; gene symbol RAD54L2.
- Organism: Homo sapiens.
- Length: 1467 amino acids.
- Top disease associations (Open Targets): asthma, allergic rhinitis and blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Helicase ARIP4 |
|---|---|
| UniProt accession | Q9Y4B4 |
| Gene | RAD54L2 |
| Organism | Homo sapiens |
| Length | 1467 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (42)
Diseases linked to this target (Open Targets).
- asthma · score 0.09
- allergic rhinitis · score 0.08
- blood protein measurement · score 0.08
- self reported educational attainment · score 0.06
- sitting height measurement · score 0.05
- testosterone measurement · score 0.04
- neutrophil percentage of granulocytes · score 0.04
- intelligence · score 0.04
- schizophrenia · score 0.04
- sex hormone-binding globulin measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y4B4-F1 | alphafold | PREDICTED | 60.62 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y4B4.
Amino-acid sequence (1467 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RAD54L2?
The strongest Open Targets associations for RAD54L2 are asthma, allergic rhinitis, blood protein measurement, self reported educational attainment and sitting height measurement.
How long is the RAD54L2 protein?
The Homo sapiens RAD54L2 protein (UniProt Q9Y4B4) is 1467 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y4B4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y4B4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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