DDB1- and CUL4-associated factor 1 (DCAF1)
Homo sapiens — UniProt Q9Y4B6
Data last refreshed: (UniProt release unknown)
Key facts
DDB1- and CUL4-associated factor 1 (DCAF1) is a protein from Homo sapiens identified by UniProt accession Q9Y4B6, 1507 residues long. MolForge cross-references it against 0 known binders and 59 disease associations.
- UniProt accession: Q9Y4B6; gene symbol DCAF1.
- Organism: Homo sapiens.
- Length: 1507 amino acids.
- Top disease associations (Open Targets): blood protein measurement, self reported educational attainment and eosinophil count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | DDB1- and CUL4-associated factor 1 |
|---|---|
| UniProt accession | Q9Y4B6 |
| Gene | DCAF1 |
| Organism | Homo sapiens |
| Length | 1507 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (59)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.12
- self reported educational attainment · score 0.12
- eosinophil count · score 0.12
- mathematical ability · score 0.10
- neoplasm · score 0.10
- body height · score 0.09
- cancer · score 0.08
- melanoma · score 0.08
- asthma · score 0.08
- HIV-1 infection · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y4B6-F1 | alphafold | PREDICTED | 74.93 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y4B6.
Amino-acid sequence (1507 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DCAF1?
The strongest Open Targets associations for DCAF1 are blood protein measurement, self reported educational attainment, eosinophil count, mathematical ability and neoplasm.
How long is the DCAF1 protein?
The Homo sapiens DCAF1 protein (UniProt Q9Y4B6) is 1507 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y4B6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y4B6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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