Malignant fibrous histiocytoma-amplified sequence 1 (MFHAS1)
Homo sapiens — UniProt Q9Y4C4
Data last refreshed: (UniProt release unknown)
Key facts
Malignant fibrous histiocytoma-amplified sequence 1 (MFHAS1) is a protein from Homo sapiens identified by UniProt accession Q9Y4C4, 1052 residues long. MolForge cross-references it against 0 known binders and 177 disease associations.
- UniProt accession: Q9Y4C4; gene symbol MFHAS1.
- Organism: Homo sapiens.
- Length: 1052 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, mathematical ability and age at first sexual intercourse measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Malignant fibrous histiocytoma-amplified sequence 1 |
|---|---|
| UniProt accession | Q9Y4C4 |
| Gene | MFHAS1 |
| Organism | Homo sapiens |
| Length | 1052 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (177)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.49
- mathematical ability · score 0.42
- age at first sexual intercourse measurement · score 0.42
- neuroticism measurement · score 0.40
- glomerular filtration rate · score 0.38
- electrocardiography · score 0.37
- diet measurement · score 0.35
- hypertension · score 0.33
- ulcerative colitis · score 0.32
- alkaline phosphatase measurement · score 0.32
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y4C4-F1 | alphafold | PREDICTED | 83.95 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y4C4.
Amino-acid sequence (1052 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MFHAS1?
The strongest Open Targets associations for MFHAS1 are neurodegenerative disease, mathematical ability, age at first sexual intercourse measurement, neuroticism measurement and glomerular filtration rate.
How long is the MFHAS1 protein?
The Homo sapiens MFHAS1 protein (UniProt Q9Y4C4) is 1052 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y4C4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y4C4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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