Carbohydrate sulfotransferase 2 (CHST2)
Homo sapiens — UniProt Q9Y4C5
Data last refreshed: (UniProt release unknown)
Key facts
Carbohydrate sulfotransferase 2 (CHST2) is a protein from Homo sapiens identified by UniProt accession Q9Y4C5, 530 residues long. MolForge cross-references it against 0 known binders and 57 disease associations.
- UniProt accession: Q9Y4C5; gene symbol CHST2.
- Organism: Homo sapiens.
- Length: 530 amino acids.
- Top disease associations (Open Targets): lymphocyte count, mean corpuscular hemoglobin and N-glycan measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Carbohydrate sulfotransferase 2 |
|---|---|
| UniProt accession | Q9Y4C5 |
| Gene | CHST2 |
| Organism | Homo sapiens |
| Length | 530 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (57)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.41
- mean corpuscular hemoglobin · score 0.27
- N-glycan measurement · score 0.26
- Red cell distribution width · score 0.25
- serum IgG glycosylation measurement · score 0.24
- monocyte count · score 0.17
- platelet component distribution width · score 0.14
- mean platelet volume · score 0.14
- reticulocyte count · score 0.13
- alkaline phosphatase measurement · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y4C5-F1 | alphafold | PREDICTED | 77.15 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y4C5.
Amino-acid sequence (530 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CHST2?
The strongest Open Targets associations for CHST2 are lymphocyte count, mean corpuscular hemoglobin, N-glycan measurement, Red cell distribution width and serum IgG glycosylation measurement.
How long is the CHST2 protein?
The Homo sapiens CHST2 protein (UniProt Q9Y4C5) is 530 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y4C5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y4C5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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