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Probable RNA-binding protein 19 (RBM19)

Homo sapiens — UniProt Q9Y4C8

Gene: RBM19Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Probable RNA-binding protein 19 (RBM19) is a protein from Homo sapiens identified by UniProt accession Q9Y4C8, 960 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.

  • UniProt accession: Q9Y4C8; gene symbol RBM19.
  • Organism: Homo sapiens.
  • Length: 960 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, body mass index and chronotype measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameProbable RNA-binding protein 19
UniProt accessionQ9Y4C8
GeneRBM19
OrganismHomo sapiens
Length960 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (45)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.50
  • body mass index · score 0.32
  • chronotype measurement · score 0.31
  • electrocardiography · score 0.27
  • substance abuse · score 0.26
  • attention deficit hyperactivity disorder · score 0.26
  • antisocial behaviour measurement · score 0.26
  • risk-taking behaviour · score 0.25
  • laryngeal squamous cell carcinoma · score 0.22
  • body weight · score 0.22

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9Y4C8-F1alphafoldPREDICTED70.03—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y4C8.

Amino-acid sequence (960 residues)

MSRLIVKNLP NGMKEERFRQ LFAAFGTLTD CSLKFTKDGK FRKFGFIGFK SEEEAQKAQK HFNKSFIDTS RITVEFCKSF GDPAKPRAWS KHAQKPSQPK QPPKDSTTPE IKKDEKKKKV AGQLEKLKED TEFQEFLSVH QRRAQAATWA NDGLDAEPSK GKSKPASDYL NFDSDSGQES EEEGAGEDLE EEASLEPKAA VQKELSDMDY LKSKMVKAGS SSSSEEEESE DEAVHCDEGS EAEEEDSSAT PVLQERDSKG AGQEQGMPAG KKRPPEARAE TEKPANQKEP TTCHTVKLRG APFNVTEKNV MEFLAPLKPV AIRIVRNAHG NKTGYIFVDF SNEEEVKQAL KCNREYMGGR YIEVFREKNV PTTKGAPKNT TKSWQGRILG ENEEEEDLAE SGRLFVRNLP YTSTEEDLEK LFSKYGPLSE LHYPIDSLTK KPKGFAFITF MFPEHAVKAY SEVDGQVFQG RMLHVLPSTI KKEASEDASA LGSSSYKKKK EAQDKANSAS SHNWNTLFMG PNAVADAIAQ KYNATKSQVF DHETKGSVAV RVALGETQLV QEVRRFLIDN GVSLDSFSQA AAERSKTVIL VKNLPAGTLA AQLQETFGHF GSLGRVLLPE GGITAIVEFL EPLEARKAFR HLAYSKFHHV PLYLEWAPVG VFSSTAPQKK KLQDTPSEPM EKDPAEPETV PDGETPEDEN PTEEGADNSS AKMEEEEEEE EEEEESLPGC TLFIKNLNFD TTEEKLKEVF SKVGTVKSCS ISKKKNKAGV LLSMGFGFVE YRKPEQAQKA LKQLQGHVVD GHKLEVRISE RATKPAVTLA RKKQVPRKQT TSKILVRNIP FQAHSREIRE LFSTFGELKT VRLPKKMTGT GTHRGFGFVD FLTKQDAKRA FNALCHSTHL YGRRLVLEWA DSEVTLQALR RKTAAHFHEP PKKKRSVVLD EILEQLEGSD SDSEEQTLQL

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with RBM19?

The strongest Open Targets associations for RBM19 are neurodegenerative disease, body mass index, chronotype measurement, electrocardiography and substance abuse.

How long is the RBM19 protein?

The Homo sapiens RBM19 protein (UniProt Q9Y4C8) is 960 amino acids long.

Browse: Targets: R · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9Y4C8
GeneRBM19
OrganismHomo sapiens
Length960
Binders0
Diseases45
View on UniProt