WD repeat-containing protein 7 (WDR7)
Homo sapiens — UniProt Q9Y4E6
Data last refreshed: (UniProt release unknown)
Key facts
WD repeat-containing protein 7 (WDR7) is a protein from Homo sapiens identified by UniProt accession Q9Y4E6, 1490 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.
- UniProt accession: Q9Y4E6; gene symbol WDR7.
- Organism: Homo sapiens.
- Length: 1490 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, systolic blood pressure and type 2 diabetes mellitus.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | WD repeat-containing protein 7 |
|---|---|
| UniProt accession | Q9Y4E6 |
| Gene | WDR7 |
| Organism | Homo sapiens |
| Length | 1490 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (45)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.30
- systolic blood pressure · score 0.29
- type 2 diabetes mellitus · score 0.28
- mean arterial pressure · score 0.21
- pulse pressure measurement · score 0.21
- neurofibrillary tangles measurement · score 0.16
- DNA methylation · score 0.14
- mathematical ability · score 0.14
- vital capacity · score 0.13
- balding measurement · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y4E6-F1 | alphafold | PREDICTED | 73.79 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y4E6.
Amino-acid sequence (1490 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with WDR7?
The strongest Open Targets associations for WDR7 are neurodegenerative disease, systolic blood pressure, type 2 diabetes mellitus, mean arterial pressure and pulse pressure measurement.
How long is the WDR7 protein?
The Homo sapiens WDR7 protein (UniProt Q9Y4E6) is 1490 amino acids long.
Browse: Targets: W · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y4E6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y4E6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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