FERM, ARHGEF and pleckstrin domain-containing protein 1 (FARP1)
Homo sapiens — UniProt Q9Y4F1
Data last refreshed: (UniProt release unknown)
Key facts
FERM, ARHGEF and pleckstrin domain-containing protein 1 (FARP1) is a protein from Homo sapiens identified by UniProt accession Q9Y4F1, 1045 residues long. MolForge cross-references it against 0 known binders and 83 disease associations.
- UniProt accession: Q9Y4F1; gene symbol FARP1.
- Organism: Homo sapiens.
- Length: 1045 amino acids.
- Top disease associations (Open Targets): coronary artery disease, PHF-tau measurement and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | FERM, ARHGEF and pleckstrin domain-containing protein 1 |
|---|---|
| UniProt accession | Q9Y4F1 |
| Gene | FARP1 |
| Organism | Homo sapiens |
| Length | 1045 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (83)
Diseases linked to this target (Open Targets).
- coronary artery disease · score 0.37
- PHF-tau measurement · score 0.36
- neurodegenerative disease · score 0.36
- self reported educational attainment · score 0.35
- mathematical ability · score 0.34
- gut microbiome measurement · score 0.30
- bacterial pathogen genotype measurement · score 0.30
- pneumococcal meningitis · score 0.30
- cystatin C measurement · score 0.29
- risk-taking behaviour · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y4F1-F1 | alphafold | PREDICTED | 76.01 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y4F1.
Amino-acid sequence (1045 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FARP1?
The strongest Open Targets associations for FARP1 are coronary artery disease, PHF-tau measurement, neurodegenerative disease, self reported educational attainment and mathematical ability.
How long is the FARP1 protein?
The Homo sapiens FARP1 protein (UniProt Q9Y4F1) is 1045 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y4F1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y4F1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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