Centrosomal protein of 170 kDa protein B (CEP170B)
Homo sapiens — UniProt Q9Y4F5
Data last refreshed: (UniProt release unknown)
Key facts
Centrosomal protein of 170 kDa protein B (CEP170B) is a protein from Homo sapiens identified by UniProt accession Q9Y4F5, 1589 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.
- UniProt accession: Q9Y4F5; gene symbol CEP170B.
- Organism: Homo sapiens.
- Length: 1589 amino acids.
- Top disease associations (Open Targets): Abnormal heart morphology, congenital heart disease and FEV/FVC ratio.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Centrosomal protein of 170 kDa protein B |
|---|---|
| UniProt accession | Q9Y4F5 |
| Gene | CEP170B |
| Organism | Homo sapiens |
| Length | 1589 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (15)
Diseases linked to this target (Open Targets).
- Abnormal heart morphology · score 0.15
- congenital heart disease · score 0.15
- FEV/FVC ratio · score 0.05
- essential tremor · score 0.05
- Hereditary late-onset Parkinson disease · score 0.04
- rheumatoid arthritis · score 0.03
- glioblastoma multiforme · score 0.02
- astrocytoma · score 0.01
- oligodendroglioma · score 0.01
- ciliopathy · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y4F5-F1 | alphafold | PREDICTED | 46.69 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y4F5.
Amino-acid sequence (1589 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CEP170B?
The strongest Open Targets associations for CEP170B are Abnormal heart morphology, congenital heart disease, FEV/FVC ratio, essential tremor and Hereditary late-onset Parkinson disease.
How long is the CEP170B protein?
The Homo sapiens CEP170B protein (UniProt Q9Y4F5) is 1589 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y4F5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y4F5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.