G-protein-signaling modulator 3 (GPSM3)
Homo sapiens — UniProt Q9Y4H4
Data last refreshed: (UniProt release unknown)
Key facts
G-protein-signaling modulator 3 (GPSM3) is a protein from Homo sapiens identified by UniProt accession Q9Y4H4, 160 residues long. MolForge cross-references it against 0 known binders and 97 disease associations.
- UniProt accession: Q9Y4H4; gene symbol GPSM3.
- Organism: Homo sapiens.
- Length: 160 amino acids.
- Top disease associations (Open Targets): lymphocyte count, leukocyte count and susceptibility to scarlet fever measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | G-protein-signaling modulator 3 |
|---|---|
| UniProt accession | Q9Y4H4 |
| Gene | GPSM3 |
| Organism | Homo sapiens |
| Length | 160 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (97)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.46
- leukocyte count · score 0.24
- susceptibility to scarlet fever measurement · score 0.24
- mean corpuscular hemoglobin · score 0.22
- inflammatory bowel disease · score 0.16
- glomerular filtration rate · score 0.14
- mean corpuscular volume · score 0.12
- hip circumference · score 0.12
- body mass index · score 0.11
- blood protein measurement · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y4H4-F1 | alphafold | PREDICTED | 71.15 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y4H4.
Amino-acid sequence (160 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GPSM3?
The strongest Open Targets associations for GPSM3 are lymphocyte count, leukocyte count, susceptibility to scarlet fever measurement, mean corpuscular hemoglobin and inflammatory bowel disease.
How long is the GPSM3 protein?
The Homo sapiens GPSM3 protein (UniProt Q9Y4H4) is 160 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y4H4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y4H4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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