Tesmin (TESMIN)
Homo sapiens — UniProt Q9Y4I5
Data last refreshed: (UniProt release unknown)
Key facts
Tesmin (TESMIN) is a protein from Homo sapiens identified by UniProt accession Q9Y4I5, 508 residues long. MolForge cross-references it against 0 known binders and 139 disease associations.
- UniProt accession: Q9Y4I5; gene symbol TESMIN.
- Organism: Homo sapiens.
- Length: 508 amino acids.
- Top disease associations (Open Targets): BMI-adjusted waist circumference, azoospermia and partial chromosome Y deletion.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tesmin |
|---|---|
| UniProt accession | Q9Y4I5 |
| Gene | TESMIN |
| Organism | Homo sapiens |
| Length | 508 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (139)
Diseases linked to this target (Open Targets).
- BMI-adjusted waist circumference · score 0.29
- azoospermia · score 0.10
- partial chromosome Y deletion · score 0.09
- serum metabolite measurement · score 0.09
- spermatogenic failures 50 · score 0.09
- spermatogenic failure 25 · score 0.09
- spermatogenic failure, X-linked, 2 · score 0.09
- male infertility with teratozoospermia due to single gene mutation · score 0.08
- isochromosomy Yp · score 0.08
- high density lipoprotein cholesterol measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y4I5-F1 | alphafold | PREDICTED | 53.81 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y4I5.
Amino-acid sequence (508 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TESMIN?
The strongest Open Targets associations for TESMIN are BMI-adjusted waist circumference, azoospermia, partial chromosome Y deletion, serum metabolite measurement and spermatogenic failures 50.
How long is the TESMIN protein?
The Homo sapiens TESMIN protein (UniProt Q9Y4I5) is 508 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y4I5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y4I5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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