Hypoxia up-regulated protein 1 (HYOU1)
Homo sapiens — UniProt Q9Y4L1
Data last refreshed: (UniProt release unknown)
Key facts
Hypoxia up-regulated protein 1 (HYOU1) is a protein from Homo sapiens identified by UniProt accession Q9Y4L1, 999 residues long. MolForge cross-references it against 0 known binders and 117 disease associations.
- UniProt accession: Q9Y4L1; gene symbol HYOU1.
- Organism: Homo sapiens.
- Length: 999 amino acids.
- Top disease associations (Open Targets): granulocytopenia with immunoglobulin abnormality, neurodegenerative disease and lung adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Hypoxia up-regulated protein 1 |
|---|---|
| UniProt accession | Q9Y4L1 |
| Gene | HYOU1 |
| Organism | Homo sapiens |
| Length | 999 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (117)
Diseases linked to this target (Open Targets).
- granulocytopenia with immunoglobulin abnormality · score 0.54
- neurodegenerative disease · score 0.54
- lung adenocarcinoma · score 0.19
- cutaneous melanoma · score 0.18
- total blood protein measurement · score 0.15
- serum albumin measurement · score 0.14
- head and neck squamous cell carcinoma · score 0.12
- calcium measurement · score 0.12
- body fat percentage · score 0.10
- glioblastoma multiforme · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y4L1-F1 | alphafold | PREDICTED | 81.24 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y4L1.
Amino-acid sequence (999 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with HYOU1?
The strongest Open Targets associations for HYOU1 are granulocytopenia with immunoglobulin abnormality, neurodegenerative disease, lung adenocarcinoma, cutaneous melanoma and total blood protein measurement.
How long is the HYOU1 protein?
The Homo sapiens HYOU1 protein (UniProt Q9Y4L1) is 999 amino acids long.
Browse: Targets: H · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y4L1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y4L1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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