Cysteine protease ATG4B (ATG4B)
Homo sapiens — UniProt Q9Y4P1
Data last refreshed: (UniProt release unknown)
Key facts
Cysteine protease ATG4B (ATG4B) is a protein from Homo sapiens identified by UniProt accession Q9Y4P1, 393 residues long. MolForge cross-references it against 1 known binders and 130 disease associations.
- UniProt accession: Q9Y4P1; gene symbol ATG4B.
- Organism: Homo sapiens.
- Length: 393 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, platelet count and body mass index.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cysteine protease ATG4B |
|---|---|
| UniProt accession | Q9Y4P1 |
| Gene | ATG4B |
| Organism | Homo sapiens |
| Length | 393 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (130)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.34
- platelet count · score 0.23
- body mass index · score 0.22
- breast adenocarcinoma · score 0.18
- body weight · score 0.16
- leukocyte count · score 0.13
- neoplasm · score 0.09
- hepatocellular carcinoma · score 0.09
- temporal arteritis · score 0.08
- bone density · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y4P1-F1 | alphafold | PREDICTED | 86.19 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y4P1.
Amino-acid sequence (393 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ATG4B?
The strongest Open Targets associations for ATG4B are neurodegenerative disease, platelet count, body mass index, breast adenocarcinoma and body weight.
How long is the ATG4B protein?
The Homo sapiens ATG4B protein (UniProt Q9Y4P1) is 393 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y4P1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y4P1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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