C-C motif chemokine 27 (CCL27)
Homo sapiens — UniProt Q9Y4X3
Data last refreshed: (UniProt release unknown)
Key facts
C-C motif chemokine 27 (CCL27) is a protein from Homo sapiens identified by UniProt accession Q9Y4X3, 112 residues long. MolForge cross-references it against 0 known binders and 377 disease associations.
- UniProt accession: Q9Y4X3; gene symbol CCL27.
- Organism: Homo sapiens.
- Length: 112 amino acids.
- Top disease associations (Open Targets): ovarian cancer, head and neck squamous cell carcinoma and blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | C-C motif chemokine 27 |
|---|---|
| UniProt accession | Q9Y4X3 |
| Gene | CCL27 |
| Organism | Homo sapiens |
| Length | 112 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (377)
Diseases linked to this target (Open Targets).
- ovarian cancer · score 0.26
- head and neck squamous cell carcinoma · score 0.16
- blood protein measurement · score 0.11
- colitis · score 0.09
- COVID-19 · score 0.08
- self reported educational attainment · score 0.08
- chronic obstructive pulmonary disease · score 0.08
- multiple myeloma · score 0.08
- neoplasm · score 0.07
- body height · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y4X3-F1 | alphafold | PREDICTED | 77.24 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y4X3.
Amino-acid sequence (112 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CCL27?
The strongest Open Targets associations for CCL27 are ovarian cancer, head and neck squamous cell carcinoma, blood protein measurement, colitis and COVID-19.
How long is the CCL27 protein?
The Homo sapiens CCL27 protein (UniProt Q9Y4X3) is 112 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y4X3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y4X3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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