Peptidyl-prolyl cis-trans isomerase A-like 4A (PPIAL4A)
Homo sapiens — UniProt Q9Y536
Data last refreshed: (UniProt release unknown)
Key facts
Peptidyl-prolyl cis-trans isomerase A-like 4A (PPIAL4A) is a protein from Homo sapiens identified by UniProt accession Q9Y536, 164 residues long. MolForge cross-references it against 0 known binders and 2 disease associations.
- UniProt accession: Q9Y536; gene symbol PPIAL4A.
- Organism: Homo sapiens.
- Length: 164 amino acids.
- Top disease associations (Open Targets): breast carcinoma and chronic kidney disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Peptidyl-prolyl cis-trans isomerase A-like 4A |
|---|---|
| UniProt accession | Q9Y536 |
| Gene | PPIAL4A |
| Organism | Homo sapiens |
| Length | 164 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (2)
Diseases linked to this target (Open Targets).
- breast carcinoma · score 0.00
- chronic kidney disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y536-F1 | alphafold | PREDICTED | 96.24 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y536.
Amino-acid sequence (164 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PPIAL4A?
The strongest Open Targets associations for PPIAL4A are breast carcinoma and chronic kidney disease.
How long is the PPIAL4A protein?
The Homo sapiens PPIAL4A protein (UniProt Q9Y536) is 164 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y536 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y536 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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