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Zinc finger and SCAN domain-containing protein 21 (ZSCAN21)

Homo sapiens — UniProt Q9Y5A6

Gene: ZSCAN21Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Zinc finger and SCAN domain-containing protein 21 (ZSCAN21) is a protein from Homo sapiens identified by UniProt accession Q9Y5A6, 473 residues long. MolForge cross-references it against 0 known binders and 78 disease associations.

  • UniProt accession: Q9Y5A6; gene symbol ZSCAN21.
  • Organism: Homo sapiens.
  • Length: 473 amino acids.
  • Top disease associations (Open Targets): diet measurement, age at menarche and azoospermia.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameZinc finger and SCAN domain-containing protein 21
UniProt accessionQ9Y5A6
GeneZSCAN21
OrganismHomo sapiens
Length473 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (78)

Diseases linked to this target (Open Targets).

  • diet measurement · score 0.08
  • age at menarche · score 0.06
  • azoospermia · score 0.05
  • Female infertility due to fertilization defect · score 0.05
  • forced expiratory volume · score 0.05
  • female infertility due to oocyte meiotic arrest · score 0.04
  • hormone measurement · score 0.04
  • pulmonary fibrosis · score 0.04
  • Hydatidiform Mole · score 0.04
  • male infertility with teratozoospermia due to single gene mutation · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9Y5A6-F1alphafoldPREDICTED65.80—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5A6.

Amino-acid sequence (473 residues)

MMTKVLGMAP VLGPRPPQEQ VGPLMVKVEE KEEKGKYLPS LEMFRQRFRQ FGYHDTPGPR EALSQLRVLC CEWLRPEIHT KEQILELLVL EQFLTILPQE LQAWVQEHCP ESAEEAVTLL EDLERELDEP GHQVSTPPNE QKPVWEKISS SGTAKESPSS MQPQPLETSH KYESWGPLYI QESGEEQEFA QDPRKVRDCR LSTQHEESAD EQKGSEAEGL KGDIISVIIA NKPEASLERQ CVNLENEKGT KPPLQEAGSK KGRESVPTKP TPGERRYICA ECGKAFSNSS NLTKHRRTHT GEKPYVCTKC GKAFSHSSNL TLHYRTHLVD RPYDCKCGKA FGQSSDLLKH QRMHTEEAPY QCKDCGKAFS GKGSLIRHYR IHTGEKPYQC NECGKSFSQH AGLSSHQRLH TGEKPYKCKE CGKAFNHSSN FNKHHRIHTG EKPYWCHHCG KTFCSKSNLS KHQRVHTGEG EAP

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZSCAN21?

The strongest Open Targets associations for ZSCAN21 are diet measurement, age at menarche, azoospermia, Female infertility due to fertilization defect and forced expiratory volume.

How long is the ZSCAN21 protein?

The Homo sapiens ZSCAN21 protein (UniProt Q9Y5A6) is 473 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9Y5A6
GeneZSCAN21
OrganismHomo sapiens
Length473
Binders0
Diseases78
View on UniProt