Nucleoside diphosphate kinase 7 (NME7)
Homo sapiens — UniProt Q9Y5B8
Data last refreshed: (UniProt release unknown)
Key facts
Nucleoside diphosphate kinase 7 (NME7) is a protein from Homo sapiens identified by UniProt accession Q9Y5B8, 376 residues long. MolForge cross-references it against 0 known binders and 68 disease associations.
- UniProt accession: Q9Y5B8; gene symbol NME7.
- Organism: Homo sapiens.
- Length: 376 amino acids.
- Top disease associations (Open Targets): electrocardiography, blood coagulation disease and QT interval.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Nucleoside diphosphate kinase 7 |
|---|---|
| UniProt accession | Q9Y5B8 |
| Gene | NME7 |
| Organism | Homo sapiens |
| Length | 376 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (68)
Diseases linked to this target (Open Targets).
- electrocardiography · score 0.48
- blood coagulation disease · score 0.42
- QT interval · score 0.40
- Situs inversus totalis · score 0.37
- venous thromboembolism · score 0.30
- pulse pressure measurement · score 0.22
- handedness · score 0.17
- Ovarian Endometriosis · score 0.16
- cor pulmonale · score 0.12
- systolic blood pressure · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5B8-F1 | alphafold | PREDICTED | 93.16 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5B8.
Amino-acid sequence (376 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NME7?
The strongest Open Targets associations for NME7 are electrocardiography, blood coagulation disease, QT interval, Situs inversus totalis and venous thromboembolism.
How long is the NME7 protein?
The Homo sapiens NME7 protein (UniProt Q9Y5B8) is 376 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5B8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5B8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.