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Protocadherin beta-9 (PCDHB9)

Homo sapiens — UniProt Q9Y5E1

Gene: PCDHB9Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Protocadherin beta-9 (PCDHB9) is a protein from Homo sapiens identified by UniProt accession Q9Y5E1, 797 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.

  • UniProt accession: Q9Y5E1; gene symbol PCDHB9.
  • Organism: Homo sapiens.
  • Length: 797 amino acids.
  • Top disease associations (Open Targets): body height, esophageal squamous cell carcinoma and diabetes mellitus.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameProtocadherin beta-9
UniProt accessionQ9Y5E1
GenePCDHB9
OrganismHomo sapiens
Length797 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (13)

Diseases linked to this target (Open Targets).

  • body height · score 0.03
  • esophageal squamous cell carcinoma · score 0.02
  • diabetes mellitus · score 0.02
  • Intestinal epithelial dysplasia · score 0.01
  • gonorrhea · score 0.00
  • neoplasm · score 0.00
  • colorectal cancer · score 0.00
  • snowflake vitreoretinal degeneration · score 0.00
  • cancer · score 0.00
  • cutaneous lupus erythematosus · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9Y5E1-F1alphafoldPREDICTED81.59—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5E1.

Amino-acid sequence (797 residues)

MKTRGFSFPR QRQVLFLFLF WGVSLAGSGF GRYSVTEETE KGSFVVNLAK DLGLAEGELA ARGTRVVSDD NKQYLLLDSH TGNLLTNEKL DREKLCGPKE PCMLYFQILM DDPFQIYRAE LRVRDINDHS PVFRHKEMVL KISENTAEGT AFRLERAQDP DEGHNSIQNY TISSNSFFHI KISGSDEGMI YPELVLDKAL DREEQEELSL TLTALDGGSP SRSGTSTIRI VVLDVNDNVP QFAQALYETQ APENSPVGSL IVKVSAGDAD SGVNAEVSYS FFDASEDILT TFQINPFSGE IFLRELLDYE LVNSYKINIQ AMDGGGLSAR CTVLIKVLDS NDNPPELIIS SLSNSVAENS PGIVLAVFKI KDRDSGENGK TICYVQDNLP FFLKPSVDNF YILMTEGALD RESKAEYNIT ITVTDLGTPR LKTEHSITLQ VSDVNDNAPA FTQTSYTLFV RENNSPALHI GSVSATDRDS GTNAQVTYSL LPPQDPHLPL ASLVSINADN GHLFALRSLD YEALQAFDFR VGASDRGSPA LSSEALVRVL VLDANDNSPF VLYPLQNGSA PCTELVPRAA EPGYLVTKVV AVDGDSGQNA WLSYQLLKAT EPGLFGVWAH NGEVRTARLL SERDAAKHRL VVLVKDNGEP PRSATATLHV LLVDGFSQPY LPLPEAAPAQ AQADLLTVYL VVALASVSSL FLLSVLLFVA VRLCRRSRAA SVGRCSVPEG PFPGHLVDVS GTGTLFQSYQ YEVCLTGGSE TGEFKFLKPI TPHLPPHRGG KEIEENSTLP NSFGFNY

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with PCDHB9?

The strongest Open Targets associations for PCDHB9 are body height, esophageal squamous cell carcinoma, diabetes mellitus, Intestinal epithelial dysplasia and gonorrhea.

How long is the PCDHB9 protein?

The Homo sapiens PCDHB9 protein (UniProt Q9Y5E1) is 797 amino acids long.

Browse: Targets: P · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9Y5E1
GenePCDHB9
OrganismHomo sapiens
Length797
Binders0
Diseases13
View on UniProt