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Protocadherin beta-7 (PCDHB7)

Homo sapiens — UniProt Q9Y5E2

Gene: PCDHB7Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Protocadherin beta-7 (PCDHB7) is a protein from Homo sapiens identified by UniProt accession Q9Y5E2, 793 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.

  • UniProt accession: Q9Y5E2; gene symbol PCDHB7.
  • Organism: Homo sapiens.
  • Length: 793 amino acids.
  • Top disease associations (Open Targets): body height, myeloid white cell count and astrocytoma.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameProtocadherin beta-7
UniProt accessionQ9Y5E2
GenePCDHB7
OrganismHomo sapiens
Length793 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (10)

Diseases linked to this target (Open Targets).

  • body height · score 0.12
  • myeloid white cell count · score 0.03
  • astrocytoma · score 0.01
  • IGA glomerulonephritis · score 0.00
  • metastatic neoplasm · score 0.00
  • cancer · score 0.00
  • psoriasis · score 0.00
  • endometrial carcinoma · score 0.00
  • Sepsis · score 0.00
  • Intestinal epithelial dysplasia · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9Y5E2-F1alphafoldPREDICTED81.76—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5E2.

Amino-acid sequence (793 residues)

MEARVERAVQ KRQVLFLCVF LGMSWAGAEP LRYFVAEETE RGTFLTNLAK DLGLGVGELR ARGTRIVSDQ NMQILLLSSL TGDLLLNEKL DREELCGPRE PCVLPFQLLL EKPFQIFRAE LWVRDINDHA PVFLDREISL KILESTTPGA AFLLESAQDS DVGTNSLSNY TISPNAYFHI NVHDSGEGNI YPELVLNQVL DREEIPEFSL TLTALDGGSP PRSGTALVRI LVLDVNDNAP DFVRSLYKVQ VPENSPVGSM VVSVSARDLD TGSNGEIAYA FSYATERILK TFQINPTSGS LHLKAQLDYE AIQTYTLTIQ AKDGGGLSGK CTVVVDVTDI NDNRPELLLS SLTSPIAENS PETVVAVFRI RDRDSGNNGK TVCSIQDDVP FILKPSVENF YTLVTEKPLD RERNTEYNIT ITVTDLGTPR LKTEHNITVL VSDVNDNAPA FTQTSYTLFV RENNSPALPI GSVSATDRDS GTNAQVIYSL LPSQDPHLPL ASLVSINADN GHLFALRSLD YEALQAFEFR VGATDRGSPA LSSEALVRVL VLDANDNSPF VLYPLQNSSA PCTEPLPRAA EPGYLVTKVV AVDGDSGQNA WLSYQLLKAT EPGLFGVWAH NGEVRTARLL SERDAAKQRL VVLVKDNGEP PRSATATLHV LLVDGFSQPY LRLPEAAPDQ ANSLTVYLVV ALASVSSLFL LSVLLFVAVR LCRRSRAAPV GRCSVPEGPF PRHLVDLSGT GTLSQSYQYE VCLTGGSGTN EFKFLKPIIP NLLPQSTGRE VEENRPFQNN LGF

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with PCDHB7?

The strongest Open Targets associations for PCDHB7 are body height, myeloid white cell count, astrocytoma, IGA glomerulonephritis and metastatic neoplasm.

How long is the PCDHB7 protein?

The Homo sapiens PCDHB7 protein (UniProt Q9Y5E2) is 793 amino acids long.

Browse: Targets: P · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9Y5E2
GenePCDHB7
OrganismHomo sapiens
Length793
Binders0
Diseases10
View on UniProt