Protocadherin beta-6 (PCDHB6)
Homo sapiens — UniProt Q9Y5E3
Data last refreshed: (UniProt release unknown)
Key facts
Protocadherin beta-6 (PCDHB6) is a protein from Homo sapiens identified by UniProt accession Q9Y5E3, 794 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: Q9Y5E3; gene symbol PCDHB6.
- Organism: Homo sapiens.
- Length: 794 amino acids.
- Top disease associations (Open Targets): body height, myeloid white cell count and cholesterol-ester transfer protein deficiency.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protocadherin beta-6 |
|---|---|
| UniProt accession | Q9Y5E3 |
| Gene | PCDHB6 |
| Organism | Homo sapiens |
| Length | 794 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- body height · score 0.11
- myeloid white cell count · score 0.06
- cholesterol-ester transfer protein deficiency · score 0.03
- lung carcinoma · score 0.02
- diabetes mellitus · score 0.01
- neoplasm · score 0.01
- memory impairment · score 0.00
- calf circumference measurement · score 0.00
- snowflake vitreoretinal degeneration · score 0.00
- endometrial carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5E3-F1 | alphafold | PREDICTED | 81.61 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5E3.
Amino-acid sequence (794 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PCDHB6?
The strongest Open Targets associations for PCDHB6 are body height, myeloid white cell count, cholesterol-ester transfer protein deficiency, lung carcinoma and diabetes mellitus.
How long is the PCDHB6 protein?
The Homo sapiens PCDHB6 protein (UniProt Q9Y5E3) is 794 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5E3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5E3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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