Protocadherin beta-3 (PCDHB3)
Homo sapiens — UniProt Q9Y5E6
Data last refreshed: (UniProt release unknown)
Key facts
Protocadherin beta-3 (PCDHB3) is a protein from Homo sapiens identified by UniProt accession Q9Y5E6, 796 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: Q9Y5E6; gene symbol PCDHB3.
- Organism: Homo sapiens.
- Length: 796 amino acids.
- Top disease associations (Open Targets): leukocyte count, lung carcinoma and diabetes mellitus.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protocadherin beta-3 |
|---|---|
| UniProt accession | Q9Y5E6 |
| Gene | PCDHB3 |
| Organism | Homo sapiens |
| Length | 796 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- leukocyte count · score 0.16
- lung carcinoma · score 0.02
- diabetes mellitus · score 0.01
- neoplasm · score 0.01
- Intestinal epithelial dysplasia · score 0.00
- male infertility · score 0.00
- snowflake vitreoretinal degeneration · score 0.00
- glioblastoma multiforme · score 0.00
- nodular sclerosis Hodgkin lymphoma · score 0.00
- lung adenocarcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5E6-F1 | alphafold | PREDICTED | 81.73 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5E6.
Amino-acid sequence (796 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PCDHB3?
The strongest Open Targets associations for PCDHB3 are leukocyte count, lung carcinoma, diabetes mellitus, neoplasm and Intestinal epithelial dysplasia.
How long is the PCDHB3 protein?
The Homo sapiens PCDHB3 protein (UniProt Q9Y5E6) is 796 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5E6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5E6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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