Protocadherin beta-2 (PCDHB2)
Homo sapiens — UniProt Q9Y5E7
Data last refreshed: (UniProt release unknown)
Key facts
Protocadherin beta-2 (PCDHB2) is a protein from Homo sapiens identified by UniProt accession Q9Y5E7, 798 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.
- UniProt accession: Q9Y5E7; gene symbol PCDHB2.
- Organism: Homo sapiens.
- Length: 798 amino acids.
- Top disease associations (Open Targets): leukocyte count, atypical teratoid rhabdoid tumor and primitive neuroectodermal tumor.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protocadherin beta-2 |
|---|---|
| UniProt accession | Q9Y5E7 |
| Gene | PCDHB2 |
| Organism | Homo sapiens |
| Length | 798 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- leukocyte count · score 0.05
- atypical teratoid rhabdoid tumor · score 0.03
- primitive neuroectodermal tumor · score 0.00
- psoriasis · score 0.00
- cancer · score 0.00
- hyperplasia · score 0.00
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5E7-F1 | alphafold | PREDICTED | 81.37 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5E7.
Amino-acid sequence (798 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PCDHB2?
The strongest Open Targets associations for PCDHB2 are leukocyte count, atypical teratoid rhabdoid tumor, primitive neuroectodermal tumor, psoriasis and cancer.
How long is the PCDHB2 protein?
The Homo sapiens PCDHB2 protein (UniProt Q9Y5E7) is 798 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5E7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5E7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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