Protocadherin beta-14 (PCDHB14)
Homo sapiens — UniProt Q9Y5E9
Data last refreshed: (UniProt release unknown)
Key facts
Protocadherin beta-14 (PCDHB14) is a protein from Homo sapiens identified by UniProt accession Q9Y5E9, 798 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.
- UniProt accession: Q9Y5E9; gene symbol PCDHB14.
- Organism: Homo sapiens.
- Length: 798 amino acids.
- Top disease associations (Open Targets): mean platelet volume, clear cell renal carcinoma and hepatocellular carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protocadherin beta-14 |
|---|---|
| UniProt accession | Q9Y5E9 |
| Gene | PCDHB14 |
| Organism | Homo sapiens |
| Length | 798 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (15)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.20
- clear cell renal carcinoma · score 0.02
- hepatocellular carcinoma · score 0.02
- lung carcinoma · score 0.01
- neoplasm · score 0.01
- dysplasia · score 0.01
- diabetes mellitus · score 0.01
- pancreatic ductal adenocarcinoma · score 0.01
- cutaneous lupus erythematosus · score 0.00
- Intestinal epithelial dysplasia · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5E9-F1 | alphafold | PREDICTED | 81.63 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5E9.
Amino-acid sequence (798 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PCDHB14?
The strongest Open Targets associations for PCDHB14 are mean platelet volume, clear cell renal carcinoma, hepatocellular carcinoma, lung carcinoma and neoplasm.
How long is the PCDHB14 protein?
The Homo sapiens PCDHB14 protein (UniProt Q9Y5E9) is 798 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5E9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5E9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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