Protocadherin beta-12 (PCDHB12)
Homo sapiens — UniProt Q9Y5F1
Data last refreshed: (UniProt release unknown)
Key facts
Protocadherin beta-12 (PCDHB12) is a protein from Homo sapiens identified by UniProt accession Q9Y5F1, 795 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.
- UniProt accession: Q9Y5F1; gene symbol PCDHB12.
- Organism: Homo sapiens.
- Length: 795 amino acids.
- Top disease associations (Open Targets): protein measurement, neoplasm and calf circumference measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protocadherin beta-12 |
|---|---|
| UniProt accession | Q9Y5F1 |
| Gene | PCDHB12 |
| Organism | Homo sapiens |
| Length | 795 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (5)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.03
- neoplasm · score 0.00
- calf circumference measurement · score 0.00
- cancer · score 0.00
- Sepsis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5F1-F1 | alphafold | PREDICTED | 81.52 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5F1.
Amino-acid sequence (795 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PCDHB12?
The strongest Open Targets associations for PCDHB12 are protein measurement, neoplasm, calf circumference measurement, cancer and Sepsis.
How long is the PCDHB12 protein?
The Homo sapiens PCDHB12 protein (UniProt Q9Y5F1) is 795 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5F1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5F1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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