Protocadherin beta-1 (PCDHB1)
Homo sapiens — UniProt Q9Y5F3
Data last refreshed: (UniProt release unknown)
Key facts
Protocadherin beta-1 (PCDHB1) is a protein from Homo sapiens identified by UniProt accession Q9Y5F3, 818 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.
- UniProt accession: Q9Y5F3; gene symbol PCDHB1.
- Organism: Homo sapiens.
- Length: 818 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Familial prostate cancer and prostate carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protocadherin beta-1 |
|---|---|
| UniProt accession | Q9Y5F3 |
| Gene | PCDHB1 |
| Organism | Homo sapiens |
| Length | 818 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (9)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.32
- Familial prostate cancer · score 0.11
- prostate carcinoma · score 0.11
- prostate cancer · score 0.11
- lung carcinoma · score 0.02
- Rett syndrome · score 0.02
- neuroblastoma · score 0.01
- neoplasm · score 0.00
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5F3-F1 | alphafold | PREDICTED | 80.11 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5F3.
Amino-acid sequence (818 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PCDHB1?
The strongest Open Targets associations for PCDHB1 are neurodegenerative disease, Familial prostate cancer, prostate carcinoma, prostate cancer and lung carcinoma.
How long is the PCDHB1 protein?
The Homo sapiens PCDHB1 protein (UniProt Q9Y5F3) is 818 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5F3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5F3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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