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Protocadherin gamma-C5 (PCDHGC5)

Homo sapiens — UniProt Q9Y5F6

Gene: PCDHGC5Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Protocadherin gamma-C5 (PCDHGC5) is a protein from Homo sapiens identified by UniProt accession Q9Y5F6, 944 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.

  • UniProt accession: Q9Y5F6; gene symbol PCDHGC5.
  • Organism: Homo sapiens.
  • Length: 944 amino acids.
  • Top disease associations (Open Targets): self reported educational attainment, mean platelet volume and body mass index.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameProtocadherin gamma-C5
UniProt accessionQ9Y5F6
GenePCDHGC5
OrganismHomo sapiens
Length944 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (20)

Diseases linked to this target (Open Targets).

  • self reported educational attainment · score 0.17
  • mean platelet volume · score 0.13
  • body mass index · score 0.12
  • genetic disorder · score 0.12
  • triglyceride measurement · score 0.09
  • age at first birth measurement · score 0.04
  • refractive error measurement · score 0.03
  • alveolar rhabdomyosarcoma · score 0.03
  • mathematical ability · score 0.02
  • neoplasm · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9Y5F6-F1alphafoldPREDICTED74.41—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5F6.

Amino-acid sequence (944 residues)

MGPKTLPQLA GKWQVLCMLS LCCWGWVSGQ LRYSVVEESE PGTLVGNVAQ DLGLKMTDLL SRRLQLGSEE NGRYFSLSLM SGALAVNQKI DRESLCGAST SCLLPVQVVT EHPLELIRVE VEILDLNDNS PSFATPEREM RISESAASGA RFPLDSAQDP DVGTNTVSFY TLSPNSHFSL NVKTLKDGKP FPELVLEQQL DREAQARHQL VLTAVDGGTP ARSGTTLISV IVLDINDNAP TFQSSVLRVG IPENAPIGTL LLRLNATDPD EGTNGQLDYS FGDHTSEAVR NLFGLDPSSG AIHVLGPIDF EESRFYEIHA RARDQGQPAM EGHCVIQVDV GDVNDNAPEV LLASLANPVL ESTPVGTVVG LFNVRDRDSG RNGEVSLDIS PDLPFQIKPS ENHYSLLTSQ PLDREATSHY IIELLASDAG SPSLHKHLTI RLNISDVNDN APRFNQQLYT AYILENRPPG SLLCTVAASD PDTGDNARLT YSIVGNQVQG APASSFVYVN PEDGRIFAQR TFDYELLQML QIVVGVRDSG SPPLHANTSL HVFVLDENDN APAVLHPRPD WEHSAPQRLP RSAPPGSLVT KVTAVDADAG HNAWLSYSLL PQSTAPGLFL VSTHTGEVRT ARALLEDDSD TQQVVVLVRD NGDPSLSSTA TVLLVLEDED PEEMPKSSDF LIHPPERSDL TLYLIVALAT VSLLSLVTFT FLSAKCLQGN ADGDGGGGQC CRRQDSPSPD FYKQSSPNLQ VSSDGTLKYM EVTLRPTDSQ SHCYRTCFSP ASDGSDFTFL RPLSVQQPTA LALEPDAIRS RSNTLRERSQ QAPPNTDWRF SQAQRPGTSG SQNGDDTGTW PNNQFDTEML QAMILASASE AADGSSTLGG GAGTMGLSAR YGPQFTLQHV PDYRQNVYIP GSNATLTNAA GKRDGKAPAG GNGNKKKSGK KEKK

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with PCDHGC5?

The strongest Open Targets associations for PCDHGC5 are self reported educational attainment, mean platelet volume, body mass index, genetic disorder and triglyceride measurement.

How long is the PCDHGC5 protein?

The Homo sapiens PCDHGC5 protein (UniProt Q9Y5F6) is 944 amino acids long.

Browse: Targets: P · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9Y5F6
GenePCDHGC5
OrganismHomo sapiens
Length944
Binders0
Diseases20
View on UniProt