Protocadherin gamma-C4 (PCDHGC4)
Homo sapiens — UniProt Q9Y5F7
Data last refreshed: (UniProt release unknown)
Key facts
Protocadherin gamma-C4 (PCDHGC4) is a protein from Homo sapiens identified by UniProt accession Q9Y5F7, 938 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q9Y5F7; gene symbol PCDHGC4.
- Organism: Homo sapiens.
- Length: 938 amino acids.
- Top disease associations (Open Targets): complex neurodevelopmental disorder, genetic disorder and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protocadherin gamma-C4 |
|---|---|
| UniProt accession | Q9Y5F7 |
| Gene | PCDHGC4 |
| Organism | Homo sapiens |
| Length | 938 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- complex neurodevelopmental disorder · score 0.37
- genetic disorder · score 0.19
- mean platelet volume · score 0.14
- refractive error measurement · score 0.06
- self reported educational attainment · score 0.05
- Down syndrome · score 0.02
- Ataxia-telangiectasia · score 0.02
- Microcephaly · score 0.01
- COVID-19 · score 0.01
- neoplasm · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5F7-F1 | alphafold | PREDICTED | 74.97 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5F7.
Amino-acid sequence (938 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PCDHGC4?
The strongest Open Targets associations for PCDHGC4 are complex neurodevelopmental disorder, genetic disorder, mean platelet volume, refractive error measurement and self reported educational attainment.
How long is the PCDHGC4 protein?
The Homo sapiens PCDHGC4 protein (UniProt Q9Y5F7) is 938 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5F7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5F7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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