Protocadherin gamma-B7 (PCDHGB7)
Homo sapiens — UniProt Q9Y5F8
Data last refreshed: (UniProt release unknown)
Key facts
Protocadherin gamma-B7 (PCDHGB7) is a protein from Homo sapiens identified by UniProt accession Q9Y5F8, 929 residues long. MolForge cross-references it against 0 known binders and 36 disease associations.
- UniProt accession: Q9Y5F8; gene symbol PCDHGB7.
- Organism: Homo sapiens.
- Length: 929 amino acids.
- Top disease associations (Open Targets): mean platelet volume, genetic disorder and triglyceride measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protocadherin gamma-B7 |
|---|---|
| UniProt accession | Q9Y5F8 |
| Gene | PCDHGB7 |
| Organism | Homo sapiens |
| Length | 929 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (36)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.34
- genetic disorder · score 0.19
- triglyceride measurement · score 0.12
- Neurodevelopmental disorder · score 0.12
- self reported educational attainment · score 0.12
- age at first birth measurement · score 0.06
- breast cancer · score 0.04
- body mass index · score 0.03
- mathematical ability · score 0.03
- triple-negative breast cancer · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5F8-F1 | alphafold | PREDICTED | 75.06 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5F8.
Amino-acid sequence (929 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PCDHGB7?
The strongest Open Targets associations for PCDHGB7 are mean platelet volume, genetic disorder, triglyceride measurement, Neurodevelopmental disorder and self reported educational attainment.
How long is the PCDHGB7 protein?
The Homo sapiens PCDHGB7 protein (UniProt Q9Y5F8) is 929 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5F8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5F8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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