Protocadherin gamma-B6 (PCDHGB6)
Homo sapiens — UniProt Q9Y5F9
Data last refreshed: (UniProt release unknown)
Key facts
Protocadherin gamma-B6 (PCDHGB6) is a protein from Homo sapiens identified by UniProt accession Q9Y5F9, 930 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.
- UniProt accession: Q9Y5F9; gene symbol PCDHGB6.
- Organism: Homo sapiens.
- Length: 930 amino acids.
- Top disease associations (Open Targets): genetic disorder, mean platelet volume and Neurodevelopmental disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protocadherin gamma-B6 |
|---|---|
| UniProt accession | Q9Y5F9 |
| Gene | PCDHGB6 |
| Organism | Homo sapiens |
| Length | 930 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (18)
Diseases linked to this target (Open Targets).
- genetic disorder · score 0.19
- mean platelet volume · score 0.18
- Neurodevelopmental disorder · score 0.12
- breast carcinoma · score 0.04
- self reported educational attainment · score 0.03
- Down syndrome · score 0.03
- refractive error measurement · score 0.02
- neoplasm · score 0.02
- laryngotracheoesophageal cleft · score 0.01
- Ataxia-telangiectasia · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5F9-F1 | alphafold | PREDICTED | 75.08 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5F9.
Amino-acid sequence (930 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PCDHGB6?
The strongest Open Targets associations for PCDHGB6 are genetic disorder, mean platelet volume, Neurodevelopmental disorder, breast carcinoma and self reported educational attainment.
How long is the PCDHGB6 protein?
The Homo sapiens PCDHGB6 protein (UniProt Q9Y5F9) is 930 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5F9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5F9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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