Protocadherin gamma-B5 (PCDHGB5)
Homo sapiens — UniProt Q9Y5G0
Data last refreshed: (UniProt release unknown)
Key facts
Protocadherin gamma-B5 (PCDHGB5) is a protein from Homo sapiens identified by UniProt accession Q9Y5G0, 923 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.
- UniProt accession: Q9Y5G0; gene symbol PCDHGB5.
- Organism: Homo sapiens.
- Length: 923 amino acids.
- Top disease associations (Open Targets): genetic disorder, Neurodevelopmental disorder and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protocadherin gamma-B5 |
|---|---|
| UniProt accession | Q9Y5G0 |
| Gene | PCDHGB5 |
| Organism | Homo sapiens |
| Length | 923 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (9)
Diseases linked to this target (Open Targets).
- genetic disorder · score 0.19
- Neurodevelopmental disorder · score 0.12
- mean platelet volume · score 0.04
- self reported educational attainment · score 0.02
- infection · score 0.00
- facioscapulohumeral muscular dystrophy · score 0.00
- infect · score 0.00
- Facioscapulohumeral dystrophy · score 0.00
- ulcerative colitis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9Y5G0-F1 | alphafold | PREDICTED | 75.36 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9Y5G0.
Amino-acid sequence (923 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PCDHGB5?
The strongest Open Targets associations for PCDHGB5 are genetic disorder, Neurodevelopmental disorder, mean platelet volume, self reported educational attainment and infection.
How long is the PCDHGB5 protein?
The Homo sapiens PCDHGB5 protein (UniProt Q9Y5G0) is 923 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9Y5G0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9Y5G0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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